HFE anticorps

N° du produit ABIN499087

Cet anticorps Lapin Polyclonal détecte spécifiquement HFE dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour HFE anticorps (ABIN499087)

Antigène: HFE (Hemochromatosis (HFE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HFE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HFE anticorps

Specificité: This antibody detects endogenous levels of HLA-H protein. (region surrounding Ile104)

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur HFE

Antigène: HFE (Hemochromatosis (HFE))

Autre désignation: HFE / HLAH

Sujet: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.Synonyms: Hereditary hemochromatosis protein

Poids moléculaire: approx. 40 kDa

ID gène: 3077

NCBI Accession: NP_000401

UniProt: Q30201

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process